Lung injury aggravated in Streptozotocin-induced diabetes: an experimental study

Purpose: The aim of the study explores impact and potential mechanisms on STZ (Streptozotocin)-induced diabetes model histopathologically immunohistochemically diabetic lung fibrosis. 
 Materials Methods: In this study, 14 adult female Wistar albino rats were divided into groups seven random animals: control induced groups. a blood glucose level above 200 mg/dl was accepted as diabetes. Nine days after experiment, sacrificed under anesthesia samples taken from each. histopathological appearance evaluated histopathologic damage score performed. Apoptosis inflammation in tissues with caspase-3 IL-1β immunohistochemically.
 Results: examination, group had higher than group, there findings such vascular congestion, thickened alveolar wall, inflammatory cell infiltration. immunohistochemistry, staining group. This difference also significant terms immunoreactivity intensity. Conclusion: determined that complications due to diabetes-induced by occurred.